SCHEMBL28339243

SCHEMBL28339243

FC(F)(F)c1ccc(C=CC2CCCCC2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.57
CYP1A2 P05177 2/20 0.44
AHR P35869 1/20 0.43
PTGS1 P23219 1/20 0.43
XBP1 P17861 1/20 0.43
FBP1 P09467 1/20 0.42
NQO2 P16083 1/20 0.42
KCNH2 Q12809 1/20 0.41
HRH3 Q9Y5N1 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
HDAC3 O15379 1/20 0.41
ADAM17 P78536 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9562361 0.83 MAOB (0.55) MAOBCYP1A2AHRPTGS1FBP1
SCHEMBL9562365 0.83 MAOB (0.55) MAOBCYP1A2AHRPTGS1FBP1
SCHEMBL28341749 0.82 RAB9A (0.45) MAOBCYP1A2
Hydrochloric Acid SCHEMBL19994632 0.81 HTR2C (0.54) MAOBCYP1A2AHRPTGS1FBP1
Hydrochloric Acid SCHEMBL19994635 0.81 HTR2C (0.54) MAOBCYP1A2AHRPTGS1FBP1
SCHEMBL30987469 0.79 MAOB (0.54) MAOBPTGS1MAOA
SCHEMBL27401595 0.79 MAOB (0.50) MAOBCYP1A2AHRPTGS1FBP1
Water SCHEMBL27753765 0.78 MAOB (0.36) MAOBMAOA
SCHEMBL24188722 0.77 MAOB (0.49) MAOBCYP1A2AHRPTGS1FBP1
Hydrochloric Acid SCHEMBL30836062 0.76 MAOB (0.48) MAOBCYP1A2AHRPTGS1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362140-A Synthesis method of cyclohexyl substituted styrenes compound 浙江工业大学 2024-01-09 CN disclosed
CN-110615729-B Method for selectively generating cis-olefin by deamination coupling of secondary carbon primary amine and aryl terminal alkyne 中南大学 2020-09-15 CN disclosed
CN-110615729-A Method for selectively generating cis-olefin by deamination coupling of secondary carbon primary amine and aryl terminal alkyne 中南大学 2019-12-27 CN disclosed