Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL566696 | 0.72 | S1PR1 (0.62) | S1PR1 | |
| SCHEMBL813782 | 0.72 | S1PR1 (0.49) | S1PR1 | |
| SCHEMBL565088 | 0.60 | S1PR1 (0.59) | S1PR1 | |
| SCHEMBL566250 | 0.57 | S1PR1 (1.00) | S1PR1 | |
| SCHEMBL566239 | 0.54 | S1PR1 (1.00) | S1PR1 | |
| SCHEMBL566651 | 0.52 | S1PR1 (0.87) | S1PR1 | |
| SCHEMBL18067896 | 0.51 | ESR1 (0.42) | S1PR1 | |
| SCHEMBL566611 | 0.51 | CA12 (0.42) | — | |
| SCHEMBL10632631 | 0.51 | MAPK1 (0.61) | — | |
| SCHEMBL9261634 | 0.51 | ADRB2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042998-A1 | S1P RECEPTORS MODULATORS | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | claimed |