Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026521 | 0.97 | — | — | |
| SCHEMBL8381309 | 0.87 | EPHX2 (0.41) | — | |
| SCHEMBL21217336 | 0.87 | EPHX1 (0.39) | — | |
| SCHEMBL5226180 | 0.86 | — | — | |
| SCHEMBL6026665 | 0.86 | — | — | |
| SCHEMBL11461186 | 0.83 | KDM4E (0.44) | — | |
| SCHEMBL1153410 | 0.83 | KDM4E (0.44) | — | |
| SCHEMBL211622 | 0.83 | KDM4E (0.44) | — | |
| SCHEMBL11457855 | 0.83 | KDM4E (0.44) | — | |
| Hydrochloric Acid SCHEMBL11271861 | 0.81 | KDM4E (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8269000-B2 | Substituted pyrimidine and triazine compounds | GRUENENTHAL GMBH (DE) | 2012-09-18 | — | — | US | disclosed |
| US-20100173889-A1 | Substituted Pyrimidine and Triazine Compounds | GRUENENTHAL GMBH (DE) | 2010-07-08 | — | — | US | disclosed |