SCHEMBL28339602

SCHEMBL28339602

COc1cc(-c2ccccc2C=O)c(OC)c(OC)c1OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 8/20 0.47
ALDH1A1 P00352 4/20 0.44
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
CRHBP P24387 1/20 0.44
KMT2A Q03164 1/20 0.44
CRHR2 Q13324 1/20 0.44
TLR2 O60603 1/20 0.44
TLR1 Q15399 1/20 0.44
TLR6 Q9Y2C9 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
MCL1 Q07820 1/20 0.43
KDM4E B2RXH2 1/20 0.42
TSHR P16473 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6536509 0.85 HDAC4 (0.56) ERN1ALDH1A1MAPTTLR2TLR1
SCHEMBL11804252 0.82 ERN1 (0.57) ERN1ALDH1A1MEN1MAPTCRHBP
SCHEMBL6545157 0.81 ALDH1A1 (0.55) ERN1ALDH1A1MEN1MAPTCRHBP
SCHEMBL6536022 0.80 ERN1 (0.54) ERN1ALDH1A1TLR2TLR1TLR6
SCHEMBL2474418 0.79 ERN1 (0.57) ERN1ALDH1A1MEN1KMT2ATLR2
SCHEMBL10773626 0.79 PRMT1 (0.60) ALDH1A1MEN1MAPTCRHBPKMT2A
SCHEMBL5492569 0.77 ALDH1A1 (0.46) ERN1ALDH1A1MEN1MAPTKMT2A
SCHEMBL25622473 0.75 ERN1 (0.47) ERN1ALDH1A1TLR2TLR1TLR6
SCHEMBL3751505 0.75 ALDH1A1 (0.59) ERN1ALDH1A1MAPTTLR2TLR1
SCHEMBL27880132 0.75 ALDH1A1 (0.48) ALDH1A1MEN1MAPTCRHBPKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110849502-B Preparation method of tetramethoxyphenyl zirconium porphyrin nanotube-selenium trioxide nanosheet composite thermosensitive sensing material 浙江理工大学 2021-03-23 CN disclosed
CN-110849502-B Preparation method of tetramethoxyphenyl zirconium porphyrin nanotube-selenium trioxide nanosheet composite thermosensitive sensing material 浙江理工大学 2021-03-23 CN disclosed
CN-110849502-A Preparation method of tetramethoxyphenyl zirconium porphyrin nanotube-selenium trioxide nanosheet composite thermosensitive sensing material 浙江理工大学 2020-02-28 CN disclosed
CN-110849502-A Preparation method of tetramethoxyphenyl zirconium porphyrin nanotube-selenium trioxide nanosheet composite thermosensitive sensing material 浙江理工大学 2020-02-28 CN disclosed
CN-110724522-A Preparation method of tetramethoxyphenyl manganese porphyrin-Zn-MOF fluorescent material 浙江理工大学 2020-01-24 CN disclosed
CN-110591700-A Preparation method of tetramethoxyphenyl zirconium porphyrin high-temperature-resistant rare earth metal complex luminescent material 浙江理工大学 2019-12-20 CN disclosed