Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.85 |
| ▸ | HPGD | P15428 | 4/20 | 0.85 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | ITGAL | P20701 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.56 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.56 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TFEB | P19484 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28339655 | 1.00 | KDM4E (0.85) | KDM4EHPGDPKMITGALNPC1 | |
| SCHEMBL28339471 | 0.85 | KDM4E (0.62) | KDM4EHPGDPKMITGALNPC1 | |
| SCHEMBL28339470 | 0.85 | KDM4E (0.62) | KDM4EHPGDPKMITGALNPC1 | |
| SCHEMBL28341795 | 0.83 | HPGD (0.59) | KDM4EHPGDITGALNPC1MAPT | |
| SCHEMBL28339486 | 0.83 | HPGD (0.59) | KDM4EHPGDITGALNPC1MAPT | |
| SCHEMBL3112646 | 0.81 | HPGD (0.97) | KDM4EHPGDNPC1MAPTRAB9A | |
| SCHEMBL3112643 | 0.81 | HPGD (0.97) | KDM4EHPGDNPC1MAPTRAB9A | |
| SCHEMBL28341779 | 0.80 | RAB9A (0.56) | KDM4EHPGDITGALNPC1MAPT | |
| SCHEMBL22110827 | 0.80 | HPGD (0.80) | KDM4EHPGDNPC1MAPTRAB9A | |
| SCHEMBL28341781 | 0.80 | RAB9A (0.56) | KDM4EHPGDITGALNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483432-A | A kind of acrylic compounds and preparation method thereof, pharmaceutical composition and purposes | UNIV FUDAN | 2019-11-22 | — | — | CN | disclosed |