Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631220 | 0.92 | KMT2A (0.76) | KMT2ALMNAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL14579683 | 0.86 | CYP1A2 (0.62) | KMT2ALMNAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL23843934 | 0.85 | KMT2A (0.60) | KMT2ALMNAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL13854911 | 0.85 | LMNA (0.72) | KMT2ALMNAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL19690708 | 0.85 | HTT (0.66) | KMT2ALMNAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL14984017 | 0.84 | KMT2A (0.64) | KMT2ALMNAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL13557799 | 0.84 | KMT2A (0.64) | KMT2ALMNAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL18907050 | 0.83 | KMT2A (0.50) | KMT2ALMNAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL28370277 | 0.83 | KMT2A (0.58) | KMT2ALMNAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL3957120 | 0.83 | KMT2A (0.63) | KMT2ALMNAMAPTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621678-A | Antitumor compounds | 法马马有限公司 | 2019-12-27 | — | — | CN | disclosed |