Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23617169 | 0.89 | KDM4E (0.47) | KDM4ESMN1; SMN2ALDH1A1HSD17B10TP53 | |
| SCHEMBL23608034 | 0.86 | CHRNA7 (0.47) | KDM4ESMN1; SMN2ALDH1A1HSD17B10TP53 | |
| SCHEMBL28341774 | 0.86 | MAPK1 (0.53) | KDM4ESMN1; SMN2ALDH1A1HSD17B10TP53 | |
| SCHEMBL28880873 | 0.83 | KDM4E (0.48) | KDM4ESMN1; SMN2ALDH1A1HSD17B10TP53 | |
| SCHEMBL28344699 | 0.83 | KDM4E (0.48) | KDM4ESMN1; SMN2ALDH1A1HSD17B10TP53 | |
| SCHEMBL28344280 | 0.82 | KDM4E (0.47) | KDM4ESMN1; SMN2ALDH1A1HSD17B10TP53 | |
| SCHEMBL28344292 | 0.82 | KDM4E (0.47) | KDM4ESMN1; SMN2ALDH1A1HSD17B10TP53 | |
| SCHEMBL28344297 | 0.82 | KDM4E (0.47) | KDM4ESMN1; SMN2ALDH1A1HSD17B10TP53 | |
| SCHEMBL23629499 | 0.78 | KDM4E (0.50) | KDM4ESMN1; SMN2ALDH1A1HSD17B10TP53 | |
| SCHEMBL28344369 | 0.78 | KDM4E (0.51) | KDM4ESMN1; SMN2ALDH1A1HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627796-B | Nitrogenous heterocyclic derivative and application thereof in medicine | 北京越之康泰生物医药科技有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-110627796-A | Nitrogenous heterocyclic derivative and application thereof in medicine | 北京越之康泰生物医药科技有限公司 | 2019-12-31 | — | — | CN | disclosed |