SCHEMBL28342113

SCHEMBL28342113

O=C(c1ccccc1)C(Br)Oc1ccc(-c2ccc([CH]c3ccccc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
GAA P10253 1/20 0.42
CYP2C9 P11712 1/20 0.42
PKM P14618 1/20 0.42
CYP2C19 P33261 1/20 0.42
PPARG P37231 12/20 0.39
PPARA Q07869 10/20 0.39
DRD1 P21728 1/20 0.36
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
BCHE P06276 1/20 0.35
CYP3A4 P08684 1/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8955004 0.81 TDP1 (0.45) CYP1A2GAACYP2C9PKMCYP2C19
SCHEMBL28603617 0.79 CYP1A2 (0.42) CYP1A2GAACYP2C9PKMCYP2C19
SCHEMBL10465557 0.77 PPARG (0.49) GAAPPARGPPARAKMT2A
SCHEMBL11512926 0.77 KMT2A (0.48) CYP1A2GAACYP2C9PKMCYP2C19
SCHEMBL28701598 0.76 SRD5A2 (0.58) CYP1A2ALDH1A1LMNASMN1; SMN2MAPT
SCHEMBL29278242 0.74 SRD5A2 (0.43) ALDH1A1LMNAMAPTRAB9AKMT2A
SCHEMBL11647490 0.74 MEN1 (0.56) CYP1A2PPARGPPARAALDH1A1HTT
SCHEMBL10465555 0.71 PPARA (0.48) GAAPPARGPPARAMAPTKMT2A
SCHEMBL11513036 0.69 OGG1 (0.46) CYP1A2CYP2C9CYP2C19ALDH1A1LMNA
SCHEMBL27699375 0.66 TDP1 (0.48) GAAALDH1A1LMNARAB9ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116999396-A Modular compositions for removal of soluble biomolecules and related methods 纳米提克斯有限责任公司 2023-11-07 CN disclosed
CN-106963514-B Urinary device 科洛普拉斯特公司 2019-12-17 CN disclosed