Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20349183 | 1.00 | MAPT (0.50) | MAPTGAAMGAMSIMGAM2 | |
| SCHEMBL3853327 | 0.87 | MAPT (0.68) | MAPTGAAMGAMSIMGAM2 | |
| SCHEMBL3853323 | 0.87 | MAPT (0.68) | MAPTGAAMGAMSIMGAM2 | |
| SCHEMBL3853272 | 0.74 | GAA (0.45) | MAPTGAAMGAMSIMGAM2 | |
| Malonic Acid Diethyl Ester SCHEMBL27943809 | 0.70 | GAA (0.88) | MAPTGAAMGAMSIMGAM2 | |
| Malonic Acid Diethyl Ester SCHEMBL1331187 | 0.70 | GAA (1.00) | MAPTGAAMGAMSIMGAM2 | |
| Malonic Acid Diethyl Ester SCHEMBL1330550 | 0.70 | GAA (1.00) | MAPTGAAMGAMSIMGAM2 | |
| Malonic Acid Diethyl Ester SCHEMBL1864301 | 0.70 | GAA (1.00) | MAPTGAAMGAMSIMGAM2 | |
| Malonic Acid Diethyl Ester SCHEMBL8636 | 0.70 | GAA (1.00) | MAPTGAAMGAMSIMGAM2 | |
| Malonic Acid Diethyl Ester SCHEMBL1331824 | 0.70 | GAA (1.00) | MAPTGAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110691598-A | Metalloenzyme inhibitor compounds | 赛列尼蒂治疗(百慕大)有限公司 | 2020-01-14 | — | — | CN | disclosed |