Malonic Acid Diethyl Ester

Malonic Acid Diethyl Ester

SCHEMBL1864301

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nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 1.00
MGAM O43451 1/20 1.00
SI P14410 1/20 1.00
MGAM2 Q2M2H8 1/20 1.00
ALDH1A1 P00352 4/20 0.60
TRPA1 O75762 1/20 0.60
LMNA P02545 1/20 0.53
HSD17B10 Q99714 1/20 0.53
ALOX15 P16050 2/20 0.50
SOAT1 P35610 1/20 0.50
CYP1A2 P05177 1/20 0.50
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
TSHR P16473 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid Diethyl Ester SCHEMBL1330550 1.00 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL8636 1.00 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL1331187 1.00 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL1331824 1.00 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL1127444 0.97 GAA (0.94) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL4939828 0.97 GAA (0.94) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL4334303 0.97 GAA (0.94) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL3670061 0.97 GAA (0.94) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL11027431 0.97 GAA (0.94) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL17433571 0.97 GAA (0.94) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12474513-B2 Blue light blocking film layer and blue light blocking system EUTEC NEW MATERIALS TECHNOLOGY (SUZHOU) CO., LTD. (CN) 2025-11-18 US disclosed
CN-115819359-B Blue light preventing compound, preparation method and composition thereof 江苏裕事达新材料科技有限责任公司 2025-04-18 CN disclosed
US-20230314675-A1 BLUE LIGHT BLOCKING FILM LAYER AND BLUE LIGHT BLOCKING SYSTEM EUTEC NEW MATERIALS TECHNOLOGY (SUZHOU) CO., LTD. (CN) 2023-10-05 US disclosed
US-11062794-B2 Olfactory signature and odorant mixture having the same YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-07-13 US disclosed
EP-3500236-A1 A PRESERVATIVE MIXTURE Symrise AG (DE) 2019-06-26 EP disclosed
US-20180253534-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2018-09-06 US disclosed
WO-2018036625-A1 A PRESERVATIVE MIXTURE SYMRISE AG (DE) 2018-03-01 WO disclosed
CN-103974985-B Fluorine-containing copolymer and water-and oil-repellent agent containing the same as active ingredient 优迈特株式会社 2017-08-01 CN disclosed
EP-2537825-B1 METHOD FOR PRODUCING 1-AMINO-1-ALKOXYCARBONYL-2-VINYLCYCLOPROPANE API CORP (JP) 2016-09-14 EP disclosed
US-9061991-B2 Method for producing 1-amino-1-alkoxycarbonyl-2-vinylcyclopropane API CORPORATION (JP) 2015-06-23 US disclosed
US-20130096339-A1 METHOD FOR PRODUCING 1-AMINO-1-ALKOXYCARBONYL-2-VINYLCYCLOPROPANE API CORPORATION (JP) 2013-04-18 US disclosed
WO-2013035070-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2013-03-14 WO disclosed
EP-2537825-A1 METHOD FOR PRODUCING 1-AMINO-1-ALKOXYCARBONYL-2-VINYLCYCLOPROPANE API Corporation (JP) 2012-12-26 EP disclosed
EP-2496682-A1 DELIVERY PARTICLE The Procter & Gamble Company (US) 2012-09-12 EP disclosed
WO-2011075659-A2 FOAM HAIR COLORANT COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2011-06-23 WO disclosed
WO-2011056935-A1 DELIVERY PARTICLE THE PROCTER & GAMBLE COMPANY (US) 2011-05-12 WO disclosed
WO-2007038524-A2 COCRYSTALLIZATION METHODS SSCI, INC. (US) 2007-04-05 WO disclosed
CN-1236372-A Components and catalysts for the polymerization of olefins MONTELL TECHNOLOGY COMPANY BV (NL) 1999-11-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230314675-A1 BLUE LIGHT BLOCKING FILM LAYER AND BLUE LIGHT BLOCKING SYSTEM CRY1, CRY2, BLVRB GAA 1721/4885MGAM 2224/4885SI 2191/4885
US-20130096339-A1 METHOD FOR PRODUCING 1-AMINO-1-ALKOXYCARBONYL-2-VINYLCYCLOPROPANE HAVCR2, BCAT1, ALDH7A1 GAA 1608/4885MGAM 2079/4885SI 700/4885
US-12474513-B2 Blue light blocking film layer and blue light blocking system CRY1, CRY2, BLVRB GAA 1721/4885MGAM 2224/4885SI 2191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.