Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.50 |
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628069 | 0.92 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5950603 | 0.90 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL27760768 | 0.86 | RAB9A (0.64) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29992900 | 0.86 | RAB9A (0.64) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3421833 | 0.85 | KMT2A (0.59) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2614971 | 0.85 | MAPK14 (0.60) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL23921025 | 0.83 | KMT2A (0.56) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4401760 | 0.83 | KMT2A (0.56) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL17145052 | 0.83 | MAPT (0.70) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL18255986 | 0.81 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642779-B | 2, 6-diaryl pyridine substance and preparation method thereof | 温州大学 | 2021-04-16 | — | — | CN | disclosed |
| CN-110642779-A | 2, 6-diaryl pyridine substance and preparation method thereof | 温州大学 | 2020-01-03 | — | — | CN | disclosed |