Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | CHAT | P28329 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28136076 | 0.79 | MAOB (0.37) | MAOBCHATNFE2L2CYP19A1MAOA | |
| SCHEMBL8742114 | 0.77 | MAOB (0.35) | MAOBCHATNFE2L2CYP19A1MAOA | |
| Bromide SCHEMBL28167446 | 0.73 | MAOB (0.32) | MAOBCHAT | |
| SCHEMBL6470886 | 0.73 | MAPT (0.40) | MAOBNFE2L2ALDH1A1LMNAMAPK1 | |
| SCHEMBL28766223 | 0.70 | CYP3A4 (0.35) | CHAT | |
| SCHEMBL28343172 | 0.70 | — | — | |
| SCHEMBL11120589 | 0.67 | MAOB (0.44) | MAOBCHATNFE2L2CYP19A1MAOA | |
| SCHEMBL9715739 | 0.67 | MAOB (0.41) | MAOBCHATTRPA1ALDH1A1LMNA | |
| SCHEMBL4293336 | 0.67 | — | — | |
| SCHEMBL3214870 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590236-B | Rubber modified asphalt mixture, preparation method thereof and pavement structure | 济南市市政工程设计研究院（集团）有限责任公司 | 2022-02-15 | — | — | CN | disclosed |
| CN-110590236-A | Rubber modified asphalt mixture, preparation method thereof and pavement structure | 济南市市政工程设计研究院（集团）有限责任公司 | 2019-12-20 | — | — | CN | disclosed |