Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | CHAT | P28329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22577725 | 0.80 | HDAC4 (0.30) | HDAC4 | |
| SCHEMBL28136076 | 0.80 | MAOB (0.37) | MAOBHDAC4CHAT | |
| SCHEMBL28448162 | 0.77 | — | — | |
| SCHEMBL6243691 | 0.76 | HDAC4 (0.36) | HDAC4 | |
| SCHEMBL8742114 | 0.75 | MAOB (0.35) | MAOBHDAC4CHAT | |
| SCHEMBL28343173 | 0.73 | MAOB (0.34) | MAOBCHAT | |
| SCHEMBL1828409 | 0.73 | MAOB (0.34) | MAOBHDAC4CHAT | |
| SCHEMBL3281981 | 0.72 | CHAT (0.32) | MAOBCHAT | |
| SCHEMBL15378664 | 0.72 | MEN1 (0.32) | — | |
| Benzene SCHEMBL27774129 | 0.71 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108178813-A | A kind of preparation method of tribromo benzoic acid polymeric material | 孝感市锐思新材科技有限公司 | 2018-06-19 | — | — | CN | disclosed |
| CN-107138142-A | A kind of preparation method of phenylstilbene bromide scarvenger | 王琪宇 | 2017-09-08 | — | — | CN | disclosed |