Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 17/20 | 0.59 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.58 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.58 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.53 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29631642 | 1.00 | FYN (0.59) | FYNCHEK2CHEK1TGFBR1ACVR1 | |
| SCHEMBL18832210 | 0.86 | FYN (0.65) | FYNCHEK2CHEK1TGFBR1ACVR1 | |
| SCHEMBL30505716 | 0.86 | FYN (0.65) | FYNCHEK2CHEK1TGFBR1ACVR1 | |
| SCHEMBL15334326 | 0.85 | FYN (0.60) | FYNCHEK2CHEK1TGFBR1 | |
| SCHEMBL29631737 | 0.85 | FYN (0.60) | FYNCHEK2CHEK1TGFBR1 | |
| SCHEMBL18861106 | 0.84 | FYN (0.61) | FYNCHEK2CHEK1TGFBR1ACVR1 | |
| SCHEMBL18860989 | 0.81 | FYN (0.55) | FYNCHEK2CHEK1TGFBR1 | |
| SCHEMBL21776556 | 0.80 | FYN (0.56) | FYNCHEK2CHEK1TGFBR1ACVR1 | |
| SCHEMBL18832218 | 0.79 | FYN (0.58) | FYNCHEK2CHEK1TGFBR1ACVR1 | |
| SCHEMBL29576661 | 0.79 | FYN (0.76) | FYNCHEK2CHEK1TGFBR1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520416-B | Polysubstituted pyridone derivative, preparation method and medical application thereof | 北京越之康泰生物医药科技有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-110520416-A | Polysubstituted pyridine ketones derivant, preparation method and its medical usage | BEIJING YUEZHIKANGTAI BIOMEDICINES CO LTD | 2019-11-29 | — | — | CN | disclosed |