Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983275 | 1.00 | MEN1 (0.44) | MEN1KMT2AALDH1A1ITGB3ITGA2B | |
| SCHEMBL17646306 | 1.00 | MEN1 (0.44) | MEN1KMT2AALDH1A1ITGB3ITGA2B | |
| SCHEMBL25659953 | 0.99 | TDP1 (0.44) | MEN1KMT2AALDH1A1ITGB3ITGA2B | |
| SCHEMBL19665743 | 0.87 | MEN1 (0.52) | MEN1KMT2AALDH1A1ITGB3ITGA2B | |
| SCHEMBL19982985 | 0.87 | MEN1 (0.52) | MEN1KMT2AALDH1A1ITGB3ITGA2B | |
| SCHEMBL10670788 | 0.87 | MEN1 (0.52) | MEN1KMT2AALDH1A1ITGB3ITGA2B | |
| SCHEMBL19983215 | 0.87 | MEN1 (0.45) | MEN1KMT2AALDH1A1ITGB3ITGA2B | |
| SCHEMBL19982993 | 0.87 | MEN1 (0.43) | MEN1KMT2AALDH1A1ITGB3ITGA2B | |
| SCHEMBL19983214 | 0.87 | MEN1 (0.45) | MEN1KMT2AALDH1A1ITGB3ITGA2B | |
| SCHEMBL23023506 | 0.86 | ITGB3 (0.51) | MEN1KMT2AALDH1A1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111349053-A | Inhibitors of lysine porphyromonas gingivalis protease | 库特克希米公司 | 2020-06-30 | — | — | CN | disclosed |
| CN-107108468-B | Inhibitors of lysine porphyromonas gingivalis protease | 库特克希米公司 | 2020-01-03 | — | — | CN | disclosed |