Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 12/20 | 0.73 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28344692 | 0.90 | HIF1A (0.79) | HIF1AEGLN1MEN1NPC1RAB9A | |
| SCHEMBL28347862 | 0.87 | HIF1A (0.83) | HIF1AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL28344622 | 0.85 | HIF1A (0.79) | HIF1AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL28598211 | 0.85 | HIF1A (1.00) | HIF1AEGLN1MEN1NPC1RAB9A | |
| SCHEMBL28345377 | 0.82 | HIF1A (1.00) | HIF1AMAPTMEN1NPC1RAB9A | |
| SCHEMBL28344653 | 0.82 | HIF1A (0.73) | HIF1ANPC1RAB9A | |
| SCHEMBL28345384 | 0.82 | HIF1A (0.88) | HIF1AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL28348077 | 0.81 | HIF1A (0.86) | HIF1AEGLN1MEN1NPC1RAB9A | |
| SCHEMBL28344737 | 0.81 | HIF1A (1.00) | HIF1AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL28594259 | 0.80 | HIF1A (0.84) | HIF1AMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407824-B | Aryl formamide compound and preparation method, pharmaceutical composition and application thereof | 安徽医科大学 | 2021-07-02 | — | — | CN | disclosed |
| CN-110407824-A | Aryl methanamide compounds and preparation method thereof, pharmaceutical composition and purposes | UNIV ANHUI MEDICAL | 2019-11-05 | — | — | CN | disclosed |