Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 12/20 | 0.73 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28348304 | 0.91 | HIF1A (0.81) | HIF1ANPC1RAB9A | |
| SCHEMBL28347862 | 0.87 | HIF1A (0.83) | HIF1ANPC1RAB9A | |
| SCHEMBL28344622 | 0.85 | HIF1A (0.79) | HIF1ANPC1RAB9A | |
| SCHEMBL28598211 | 0.85 | HIF1A (1.00) | HIF1ANPC1RAB9A | |
| SCHEMBL28347607 | 0.82 | HIF1A (1.00) | HIF1ANPC1RAB9AROCK2TP53 | |
| SCHEMBL28344732 | 0.82 | HIF1A (0.73) | HIF1ANPC1RAB9A | |
| SCHEMBL28345384 | 0.82 | HIF1A (0.88) | HIF1ANPC1RAB9A | |
| SCHEMBL28348077 | 0.81 | HIF1A (0.86) | HIF1ANPC1RAB9A | |
| SCHEMBL28344737 | 0.81 | HIF1A (1.00) | HIF1ANPC1RAB9A | |
| Fluorobenzene SCHEMBL28344654 | 0.81 | ROCK2 (0.51) | HIF1ANAAAROCK2DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407824-B | Aryl formamide compound and preparation method, pharmaceutical composition and application thereof | 安徽医科大学 | 2021-07-02 | — | — | CN | disclosed |
| CN-110407824-A | Aryl methanamide compounds and preparation method thereof, pharmaceutical composition and purposes | UNIV ANHUI MEDICAL | 2019-11-05 | — | — | CN | disclosed |