SCHEMBL28344879

SCHEMBL28344879

C=Cc1cc(-c2nc(Cl)cn2C2CC2)cnn1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 19/20 0.50
CYP11B1 P15538 14/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20339874 0.81 CYP11B2 (0.55) CYP11B2CYP11B1
SCHEMBL28344913 0.79 CYP11B2 (0.57) CYP11B2CYP11B1
SCHEMBL28344862 0.77 CYP11B2 (0.58) CYP11B2CYP11B1
SCHEMBL28344926 0.77 CYP11B2 (0.58) CYP11B2CYP11B1
SCHEMBL20338384 0.74 CYP11B2 (0.72) CYP11B2CYP11B1
SCHEMBL30657511 0.74 CYP11B2 (0.72) CYP11B2CYP11B1
SCHEMBL28342238 0.72 CYP11B2 (0.58) CYP11B2CYP11B1
SCHEMBL20338336 0.68 CYP11B2 (0.76) CYP11B2CYP11B1
SCHEMBL20338174 0.67 CYP11B2 (1.00) CYP11B2CYP11B1
SCHEMBL20338322 0.65 CYP11B2 (0.74) CYP11B2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110691598-A Metalloenzyme inhibitor compounds 赛列尼蒂治疗(百慕大)有限公司 2020-01-14 CN disclosed