Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.76 |
| ▸ | TP53 | P04637 | 4/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.56 |
| ▸ | PFKFB3 | Q16875 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4771303 | 0.86 | HTT (1.00) | HTTTP53ALOX12PTGS2PFKFB3 | |
| SCHEMBL17454428 | 0.85 | HTT (0.78) | HTTTP53ALOX12PTGS2PFKFB3 | |
| SCHEMBL30483538 | 0.83 | HTT (0.76) | HTTTP53ALOX12PTGS2PFKFB3 | |
| SCHEMBL17452649 | 0.81 | HTT (0.71) | HTTTP53ALOX12PTGS2PFKFB3 | |
| SCHEMBL6280740 | 0.78 | TP53 (1.00) | HTTTP53ALOX12ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6312206 | 0.76 | HTT (0.64) | HTTTP53ALOX12PTGS2PFKFB3 | |
| SCHEMBL17260096 | 0.75 | PTGS2 (0.77) | HTTTP53ALOX12PTGS2PFKFB3 | |
| SCHEMBL20604227 | 0.75 | HTT (0.72) | HTTTP53ALOX12PTGS2PFKFB3 | |
| SCHEMBL20604184 | 0.75 | HTT (0.78) | HTTTP53ALOX12PTGS2LMNA | |
| Hydrochloric Acid SCHEMBL6312200 | 0.74 | HTT (0.61) | HTTTP53ALOX12PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642837-B | Pyridine amide compound containing triazole or quinolinone structure and application thereof | 江西科技师范大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-110642837-A | Pyridine amide compound containing triazole or quinolinone structure and application thereof | 江西科技师范大学 | 2020-01-03 | — | — | CN | disclosed |