SCHEMBL28345477

SCHEMBL28345477

O=C(O)C1CCC2C=Cc3cccc4ccc1c2c34

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
HIF1A Q16665 1/20 0.34
HSD17B10 Q99714 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9355045 0.80 KDM4E (0.30) MEN1KMT2A
SCHEMBL27748031 0.76 CYP1A2 (0.35) CYP1A2CYP2D6CYP2C9CYP2C19HIF1A
SCHEMBL5871914 0.76
SCHEMBL6011282 0.74
SCHEMBL20209401 0.71 CYP1A2 (0.35) CYP1A2CYP2D6CYP2C9CYP2C19HIF1A
SCHEMBL28646516 0.69 KDM4E (0.35) HSD17B10MEN1KMT2A
SCHEMBL50690 0.69 ADRA2A (0.36) CYP1A2CYP2D6CYP2C9CYP2C19HIF1A
SCHEMBL29352264 0.69 ADRA2A (0.36) CYP1A2CYP2D6CYP2C9CYP2C19HIF1A
SCHEMBL30365719 0.69 ADRA2A (0.36) CYP1A2CYP2D6CYP2C9CYP2C19HIF1A
SCHEMBL29022395 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110709065-A Fusogenic liposomes, compositions, kits and uses thereof for treating cancer APA先进技术有限公司 2020-01-17 CN claimed
CN-110709065-B Fusogenic liposomes, compositions, kits and uses thereof for treating cancer APA先进技术有限公司 2023-02-10 CN disclosed
CN-110709065-A Fusogenic liposomes, compositions, kits and uses thereof for treating cancer APA先进技术有限公司 2020-01-17 CN disclosed