Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PDE5A | O76074 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20568334 | 0.88 | PDE5A (0.43) | KMT2AMEN1PDE5APOLBMAPK1 | |
| SCHEMBL20569128 | 0.85 | PDE5A (0.49) | KMT2AMEN1PDE5AHDAC1HDAC2 | |
| SCHEMBL20570181 | 0.82 | KMT2A (0.46) | KMT2AMEN1PDE5APOLBLMNA | |
| SCHEMBL20567831 | 0.81 | PDE5A (0.45) | KMT2AMEN1PDE5APOLBLMNA | |
| SCHEMBL20568084 | 0.77 | PDE5A (0.49) | KMT2AMEN1PDE5APOLB | |
| SCHEMBL6475154 | 0.77 | KMT2A (0.46) | KMT2AMEN1PDE5APOLBTSHR | |
| SCHEMBL6476218 | 0.76 | MAPT (0.47) | KMT2AMEN1MAPK1RAB9ARXFP1 | |
| SCHEMBL6644230 | 0.76 | KMT2A (0.53) | KMT2AMEN1PDE5APOLBTSHR | |
| SCHEMBL20569063 | 0.76 | PDE5A (0.45) | KMT2AMEN1PDE5APOLBLMNA | |
| SCHEMBL6482634 | 0.76 | KMT2A (0.44) | KMT2AMEN1PDE5APOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063458-A | Novel dual mode of action of soluble guanylate cyclase activators and phosphodiesterase inhibitors and uses thereof | 托帕杜制药公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-110621676-B | Dual mode of action of soluble guanylate cyclase activators and phosphodiesterase inhibitors and uses thereof | 托帕杜制药公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-110621676-A | Novel dual mode of action of soluble guanylate cyclase activators and phosphodiesterase inhibitors and uses thereof | 托帕杜制药公司 | 2019-12-27 | — | — | CN | disclosed |