Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PDE5A | O76074 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6476366 | 0.95 | KMT2A (0.47) | KMT2AMEN1POLBPDE5ALMNA | |
| SCHEMBL6648050 | 0.93 | KMT2A (0.45) | KMT2AMEN1POLBPDE5ALMNA | |
| SCHEMBL6482634 | 0.91 | KMT2A (0.44) | KMT2AMEN1POLBPDE5ALMNA | |
| SCHEMBL20567831 | 0.90 | PDE5A (0.45) | KMT2AMEN1POLBPDE5ALMNA | |
| SCHEMBL6642309 | 0.89 | KMT2A (0.45) | KMT2AMEN1POLBPDE5ALMNA | |
| SCHEMBL6644709 | 0.88 | KMT2A (0.44) | KMT2AMEN1POLBPDE5ALMNA | |
| SCHEMBL6641002 | 0.88 | KMT2A (0.50) | KMT2AMEN1POLBPDE5ALMNA | |
| SCHEMBL6641750 | 0.88 | KMT2A (0.46) | KMT2AMEN1POLBPDE5ALMNA | |
| SCHEMBL20570181 | 0.88 | KMT2A (0.46) | KMT2AMEN1POLBPDE5ALMNA | |
| SCHEMBL6641264 | 0.87 | PDE5A (0.43) | KMT2AMEN1POLBPDE5ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6962911-B2 | Pyrrolopyrimidinone derivatives, process of preparation and use | SK CHEMICALS CO., LTD. (KR) | 2005-11-08 | — | — | US | disclosed |
| EP-1257553-B1 | PYRROLOPYRIMIDINONE DERIVATIVES, PROCESS OF PREPARATION AND USE | SK CHEMICALS CO LTD (KR) | 2004-05-26 | — | — | EP | disclosed |