Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.60 |
| ▸ | CA1 | P00915 | 4/20 | 0.60 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5404794 | 0.84 | CA2 (0.58) | CA2CA1MAPK1SLC1A2SLC1A1 | |
| SCHEMBL5404803 | 0.84 | CA2 (0.58) | CA2CA1MAPK1SLC1A2SLC1A1 | |
| SCHEMBL8011314 | 0.81 | CA2 (0.64) | CA2CA1GRIK1GRIK2MAPK1 | |
| SCHEMBL2369450 | 0.80 | CA2 (0.82) | CA2CA1GRIK1GRIK2MAPK1 | |
| SCHEMBL28191059 | 0.79 | CA2 (0.62) | CA2CA1GRIK1GRIK2MAPK1 | |
| SCHEMBL9321230 | 0.79 | CA2 (0.52) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL7638666 | 0.78 | CA2 (0.78) | CA2CA1GRIK1GRIK2MAPK1 | |
| Hydrochloric Acid SCHEMBL3023637 | 0.78 | CA2 (0.78) | CA2CA1GRIK1GRIK2MAPK1 | |
| SCHEMBL6947583 | 0.76 | CA2 (0.75) | CA2CA1GRIK1GRIK2MAPK1 | |
| SCHEMBL3977147 | 0.76 | CA2 (0.75) | CA2CA1GRIK1GRIK2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110650738-B | Compounds and methods for treating parasitic diseases | 博德研究所 | 2023-05-09 | — | — | CN | disclosed |
| CN-110650738-A | Compounds and methods for treating parasitic diseases | 博德研究所 | 2020-01-03 | — | — | CN | disclosed |