Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 9/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 7/20 | 0.52 |
| ▸ | PSMB2 | P49721 | 7/20 | 0.52 |
| ▸ | PSMB11 | A5LHX3 | 6/20 | 0.52 |
| ▸ | PSMA7 | O14818 | 6/20 | 0.52 |
| ▸ | PSMA1 | P25786 | 6/20 | 0.52 |
| ▸ | PSMA2 | P25787 | 6/20 | 0.52 |
| ▸ | PSMA3 | P25788 | 6/20 | 0.52 |
| ▸ | PSMA4 | P25789 | 6/20 | 0.52 |
| ▸ | PSMB8 | P28062 | 6/20 | 0.52 |
| ▸ | PSMB9 | P28065 | 6/20 | 0.52 |
| ▸ | PSMA5 | P28066 | 6/20 | 0.52 |
| ▸ | PSMB4 | P28070 | 6/20 | 0.52 |
| ▸ | PSMB6 | P28072 | 6/20 | 0.52 |
| ▸ | PSMB10 | P40306 | 6/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28345790 | 1.00 | PSMB5 (0.69) | PSMB5ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL28345993 | 0.88 | PSMB5 (0.53) | PSMB5ALDH1A1PSMB1PSMB2PSMB11 | |
| SCHEMBL28345997 | 0.88 | PSMB5 (0.53) | PSMB5ALDH1A1PSMB1PSMB2PSMB11 | |
| SCHEMBL28349239 | 0.87 | PSMB5 (0.60) | PSMB5ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL28349240 | 0.87 | PSMB5 (0.60) | PSMB5ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL28345825 | 0.86 | PSMB5 (0.56) | PSMB5ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL28345824 | 0.86 | PSMB5 (0.56) | PSMB5ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL2127966 | 0.85 | PSMB5 (0.69) | PSMB5PSMB1PSMB2PSMB11PSMA7 | |
| SCHEMBL1913564 | 0.83 | PSMB5 (0.72) | PSMB5PSMB1PSMB2PSMB11PSMA7 | |
| SCHEMBL2128457 | 0.83 | PSMB5 (0.72) | PSMB5PSMB1PSMB2PSMB11PSMA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108929340-B | Proline boric acid compound and preparation method and application thereof | 北京大学 | 2019-12-13 | — | — | CN | disclosed |