Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28349240 | 1.00 | PSMB5 (0.60) | PSMB5ATMALDH1A1THRBCYP2C9 | |
| SCHEMBL28345793 | 0.87 | PSMB5 (0.69) | PSMB5ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL28345790 | 0.87 | PSMB5 (0.69) | PSMB5ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL3932153 | 0.87 | PSMB5 (0.61) | PSMB5ALDH1A1THRBHSD17B10CTSL | |
| SCHEMBL3932148 | 0.87 | PSMB5 (0.61) | PSMB5ALDH1A1THRBHSD17B10CTSL | |
| SCHEMBL28345825 | 0.85 | PSMB5 (0.56) | PSMB5ATMALDH1A1THRBCYP2C9 | |
| SCHEMBL28345824 | 0.85 | PSMB5 (0.56) | PSMB5ATMALDH1A1THRBCYP2C9 | |
| SCHEMBL28147568 | 0.84 | PSMB5 (0.59) | PSMB5ALDH1A1THRBCTSLMEN1 | |
| SCHEMBL3083268 | 0.80 | CTSL (0.69) | PSMB5ATMALDH1A1THRBCYP2C9 | |
| SCHEMBL2125371 | 0.80 | CTSL (0.69) | PSMB5ATMALDH1A1THRBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108929340-B | Proline boric acid compound and preparation method and application thereof | 北京大学 | 2019-12-13 | — | — | CN | disclosed |