SCHEMBL28346236

SCHEMBL28346236

CC(C)([SiH2]n1ccnc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 4/20 0.47
CYP11B2 P19099 4/20 0.47
CYP17A1 P05093 6/20 0.41
CYP19A1 P11511 5/20 0.40
CYP3A4 P08684 3/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2D6 P10635 2/20 0.39
MAPT P10636 2/20 0.39
TBXAS1 P24557 2/20 0.39
NR1I2 O75469 2/20 0.39
ADORA3 P0DMS8 2/20 0.39
TBXA2R P21731 2/20 0.39
CCKBR P32239 2/20 0.39
OPRK1 P41145 2/20 0.39
SLC6A3 Q01959 2/20 0.39
KCNH2 Q12809 2/20 0.39
NR1H4 Q96RI1 2/20 0.39
MEN1 O00255 2/20 0.39
ALOX15 P16050 2/20 0.39
TSHR P16473 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL918579 0.73 NFKB1 (0.39) CYP17A1CYP19A1NFKB1QPCTQPCTL
SCHEMBL29201351 0.69 CYP11B1 (0.67) CYP11B1CYP11B2CYP17A1CYP19A1CYP3A4
Bromide SCHEMBL29201437 0.68 CYP11B1 (0.65) CYP11B1CYP11B2CYP17A1CYP19A1CYP3A4
Hydrochloric Acid SCHEMBL29201340 0.68 CYP11B1 (0.65) CYP11B1CYP11B2CYP17A1CYP19A1CYP3A4
Iodide SCHEMBL29201305 0.68 CYP11B1 (0.65) CYP11B1CYP11B2CYP17A1CYP19A1CYP3A4
SCHEMBL11592827 0.67 NFKB1 (0.33) CYP19A1NFKB1QPCTQPCTL
SCHEMBL918937 0.67 NFKB1 (0.33) CYP17A1TBXAS1NFKB1QPCTQPCTL
SCHEMBL7286575 0.67 CYP17A1 (0.49) CYP11B1CYP11B2CYP17A1CYP19A1CYP3A4
SCHEMBL27477705 0.67 CYP11B1 (0.62) CYP11B1CYP11B2CYP17A1CYP19A1CYP3A4
SCHEMBL11373170 0.67 CYP11B1 (0.62) CYP11B1CYP11B2CYP17A1CYP19A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110551151-A preparation method of phosphate or phosphite ester, electrolyte and secondary battery MICROVAST POWER SYSTEMS CO LTD 2019-12-10 CN disclosed