Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28346605 | 0.78 | CES1 (0.34) | — | |
| SCHEMBL9839461 | 0.71 | CDC25B (0.41) | — | |
| SCHEMBL27899888 | 0.70 | KDM1A (0.30) | KDM1ANOTUM | |
| SCHEMBL29634371 | 0.69 | CDC25B (0.44) | NOTUM | |
| SCHEMBL28968222 | 0.69 | CDC25B (0.44) | NOTUM | |
| SCHEMBL4555546 | 0.68 | CES1 (0.56) | — | |
| SCHEMBL15532163 | 0.66 | KDM1A (0.33) | KDM1A | |
| SCHEMBL6705993 | 0.65 | KDM1A (0.39) | KDM1ANOTUMCA1CA2CA9 | |
| SCHEMBL817540 | 0.64 | KDM1A (0.38) | KDM1ANOTUM | |
| SCHEMBL29514638 | 0.63 | ROCK1 (0.41) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106983751-B | Bicyclic substituted uracils and their use | 拜耳医药股份有限公司 | 2020-01-07 | — | — | CN | disclosed |