Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.38 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31437683 | 0.74 | EEF2K (0.42) | CDC25BIDO1MAOAMAOBAKT1 | |
| SCHEMBL7932433 | 0.72 | CES1 (0.42) | MAOAMAOBGLAPOLBCES1 | |
| SCHEMBL22070109 | 0.72 | ALOX15 (0.42) | GLAPOLBGAATSHRCES1 | |
| SCHEMBL28346540 | 0.71 | KDM1A (0.30) | — | |
| SCHEMBL28346605 | 0.71 | CES1 (0.34) | CES1 | |
| SCHEMBL6754916 | 0.69 | POLB (0.41) | IDO1GLAPOLBGAATSHR | |
| SCHEMBL28968222 | 0.69 | CDC25B (0.44) | CDC25BIDO1MAOAMAOBAKT1 | |
| SCHEMBL29634371 | 0.69 | CDC25B (0.44) | CDC25BIDO1MAOAMAOBAKT1 | |
| SCHEMBL9243271 | 0.66 | NPC1 (0.39) | CDC25BPOLBTSHRCES1MCL1 | |
| SCHEMBL9737187 | 0.64 | CA12 (0.32) | CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011944-A | Substituted α-pyrones | CIBA-GEIGY CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0344113-A2 | Substituted alpha-pyrones and naphthoquinones | CIBA-GEIGY AG (CH) | 1989-11-29 | — | — | EP | disclosed |