Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.83 |
| ▸ | TSHR | P16473 | 5/20 | 0.83 |
| ▸ | LMNA | P02545 | 3/20 | 0.83 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | AHR | P35869 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 6/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | CASP1 | P29466 | 3/20 | 0.51 |
| ▸ | CASP7 | P55210 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KLK7 | P49862 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13889179 | 0.99 | MAPT (0.81) | MAPTTSHRLMNACREBBPMAPK1 | |
| SCHEMBL28344302 | 0.93 | MAPT (0.72) | MAPTTSHRLMNACREBBPMAPK1 | |
| SCHEMBL28344116 | 0.85 | MAPT (0.65) | MAPTTSHRLMNACREBBPMAPK1 | |
| SCHEMBL28347742 | 0.84 | MAPT (0.64) | MAPTTSHRLMNACREBBPMAPK1 | |
| SCHEMBL13888981 | 0.83 | POLB (0.78) | MAPTTSHRLMNACREBBPMAPK1 | |
| SCHEMBL9706173 | 0.80 | MAPT (0.64) | MAPTTSHRLMNACREBBPMAPK1 | |
| SCHEMBL13889175 | 0.78 | POLB (0.75) | MAPTTSHRLMNACREBBPMAPK1 | |
| SCHEMBL28344126 | 0.78 | POLB (0.56) | MAPTTSHRLMNACREBBPMAPK1 | |
| Dimethylamine SCHEMBL9706176 | 0.77 | MAPT (0.67) | MAPTTSHRLMNACREBBPMAPK1 | |
| SCHEMBL28344840 | 0.77 | POLB (0.55) | MAPTTSHRLMNACREBBPMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110540541-A | 6H-indolo [2,3-b ] quinoxaline compound and preparation method and application thereof | UNIV GUANGXI NORMAL | 2019-12-06 | — | — | CN | disclosed |