Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | TSHR | P16473 | 5/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.65 |
| ▸ | USP2 | O75604 | 3/20 | 0.65 |
| ▸ | CASP1 | P29466 | 3/20 | 0.65 |
| ▸ | CASP7 | P55210 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL9706172 | 0.85 | MAPT (0.92) | MAPTL3MBTL1KDM4ETDP1MAPK1 | |
| Dimethylamine SCHEMBL9706140 | 0.85 | MAPT (0.66) | MAPTL3MBTL1KDM4ETDP1MAPK1 | |
| Dimethylamine SCHEMBL9706158 | 0.84 | MAPT (0.60) | MAPTL3MBTL1KDM4ETDP1MAPK1 | |
| Dimethylamine SCHEMBL9706312 | 0.84 | MAPT (0.71) | MAPTL3MBTL1KDM4ETDP1MAPK1 | |
| SCHEMBL13165173 | 0.81 | MAPT (0.71) | MAPTL3MBTL1KDM4ETDP1MAPK1 | |
| SCHEMBL13889175 | 0.80 | POLB (0.75) | MAPTL3MBTL1KDM4ETDP1MAPK1 | |
| Dimethylamine SCHEMBL1581069 | 0.80 | MAPT (0.71) | MAPTL3MBTL1KDM4ETDP1MAPK1 | |
| SCHEMBL5524713 | 0.79 | MAPT (1.00) | MAPTL3MBTL1KDM4ETDP1MAPK1 | |
| SCHEMBL9706173 | 0.79 | MAPT (0.64) | MAPTL3MBTL1KDM4ETDP1MAPK1 | |
| SCHEMBL28347141 | 0.77 | MAPT (0.83) | MAPTL3MBTL1KDM4ETDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238459-B1 | SUBSTITUTED INDOLOQUINOXALINES | Lundblad, Leif (SE) | 1992-04-15 | — | — | EP | disclosed |
| US-4990510-A | Viricides, anticancer agents | LEIF LUNDBLAD (BE) | 1991-02-05 | — | — | US | disclosed |
| EP-0238459-A1 | Substituted indoloquinoxalines | Lundblad, Leif (SE) | 1987-09-23 | — | — | EP | disclosed |
| WO-1987004436-A1 | SUBSTITUTED INDOLOQUINOXALINES | LUNDBLAD, LEIF (SE) | 1987-07-30 | — | — | WO | disclosed |