Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20214050 | 0.90 | KDM4E (0.35) | PTGER1MYCWDR5PTGDR2DHODH | |
| SCHEMBL29580277 | 0.84 | PTGER1 (0.38) | PTGER1KDM4EMEN1KMT2APTGS2 | |
| SCHEMBL20224694 | 0.84 | PTGER1 (0.37) | PTGER1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL20214266 | 0.84 | PTGER1 (0.38) | PTGER1KDM4EMEN1KMT2APTGS2 | |
| SCHEMBL18295289 | 0.82 | GRIA4 (0.36) | PTGER1MYCWDR5DHODHGRIA4 | |
| SCHEMBL18282149 | 0.82 | ALDH1A1 (0.34) | PTGER1MYCWDR5DHODHKDM4E | |
| SCHEMBL29231587 | 0.81 | PTGER1 (0.38) | PTGER1MYCWDR5PTGDR2DHODH | |
| SCHEMBL18282156 | 0.81 | NPC1 (0.37) | PTGER1MYCWDR5PTGDR2DHODH | |
| SCHEMBL20214527 | 0.80 | F2RL3 (0.33) | PTGER1MYCWDR5DHODHKDM4E | |
| SCHEMBL18282046 | 0.80 | PTGER1 (0.35) | PTGER1MYCWDR5PTGDR2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110603254-B | Substituted pyrazole compounds and methods of using the same for treating hyperproliferative diseases | 班塔姆制药有限责任公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-110603254-A | Substituted pyrazole compounds and methods of using the same for treating hyperproliferative diseases | 班塔姆制药有限责任公司 | 2019-12-20 | — | — | CN | disclosed |