SCHEMBL28347264

SCHEMBL28347264

O=[N+]([O-])OC(CP(=O)(c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.59
NPC1 O15118 1/20 0.45
ADAM17 P78536 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 3/20 0.39
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
LMNA P02545 1/20 0.38
CYP3A4 P08684 1/20 0.37
CYP2C19 P33261 1/20 0.37
GAA P10253 2/20 0.37
MAPT P10636 1/20 0.37
ALPG P10696 1/20 0.37
ALOX12 P18054 1/20 0.37
NPY1R P25929 1/20 0.37
HTT P42858 1/20 0.37
NPY2R P49146 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28350770 0.87 GSR (0.46) GSRNPC1ADAM17L3MBTL1ALDH1A1
SCHEMBL28350596 0.87 GSR (0.46) GSRNPC1ADAM17MEN1KMT2A
SCHEMBL28347265 0.87 GSR (0.46) GSRNPC1ADAM17ALDH1A1MEN1
SCHEMBL28350897 0.82 GSR (0.43) GSRNPC1ADAM17L3MBTL1ALDH1A1
SCHEMBL28047729 0.76 GSR (0.71) GSRNPC1ADAM17ALDH1A1MEN1
SCHEMBL28215784 0.75 GSR (0.69) GSRNPC1ADAM17ALDH1A1MEN1
SCHEMBL27319378 0.75 GSR (0.69) GSRNPC1ADAM17ALDH1A1MEN1
SCHEMBL9803273 0.73 GSR (0.67) GSRNPC1ADAM17ALDH1A1KMT2A
SCHEMBL28885399 0.72 GSR (0.65) GSRNPC1ADAM17ALDH1A1LMNA
SCHEMBL28958827 0.72 GSR (0.65) GSRNPC1ADAM17ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107973819-B beta-phosphorylated nitrate compound and preparation method thereof 烟台大学 2019-12-17 CN disclosed