SCHEMBL28350596

SCHEMBL28350596

O=[N+]([O-])OC(CP(=O)(c1ccccc1)c1ccccc1)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.46
ACP3 P15309 1/20 0.42
CYP2C19 P33261 3/20 0.38
TP53 P04637 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2C9 P11712 2/20 0.38
TSHR P16473 2/20 0.38
SLC6A4 P31645 4/20 0.38
SLC6A2 P23975 3/20 0.38
SLC6A3 Q01959 3/20 0.38
KCNK2 O95069 2/20 0.38
KCNH2 Q12809 2/20 0.38
CACNA1C Q13936 2/20 0.38
CNR2 P34972 1/20 0.37
HTR1A P08908 1/20 0.37
NPC1 O15118 4/20 0.36
SLC7A5 Q01650 4/20 0.36
RAB9A P51151 3/20 0.36
HRH3 Q9Y5N1 2/20 0.36
CYP2D6 P10635 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28347264 0.87 GSR (0.59) GSRCYP2C19CYP3A4NPC1MEN1
SCHEMBL28350770 0.80 GSR (0.46) GSRNPC1MEN1KMT2AADAM17
SCHEMBL28347265 0.78 GSR (0.46) GSRACP3SLC6A4SLC6A2NPC1
SCHEMBL28347506 0.76 GSR (0.47) GSRACP3CYP2C19TP53CYP3A4
SCHEMBL28350897 0.74 GSR (0.43) GSRACP3CYP2C19CYP3A4NPC1
SCHEMBL28047729 0.65 GSR (0.71) GSRCYP3A4CNR2NPC1MEN1
SCHEMBL27319378 0.64 GSR (0.69) GSRSLC6A4NPC1MEN1KMT2A
SCHEMBL28215784 0.64 GSR (0.69) GSRACP3CNR2NPC1MEN1
SCHEMBL30266040 0.64 ACP3 (0.53) ACP3CYP2C19TP53CYP3A4CYP2C9
SCHEMBL9803273 0.63 GSR (0.67) GSRNPC1CYP2D6KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107973819-B beta-phosphorylated nitrate compound and preparation method thereof 烟台大学 2019-12-17 CN disclosed