Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30298332 | 0.97 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ANOS3NOS1 | |
| SCHEMBL413656 | 0.97 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ANOS3NOS1 | |
| SCHEMBL31326515 | 0.81 | MEN1 (0.38) | ALDH1A1MEN1KMT2ANOS3NOS1 | |
| SCHEMBL13080849 | 0.81 | SLC6A2 (0.48) | ALDH1A1MEN1KMT2ANOS3NOS1 | |
| SCHEMBL2215264 | 0.81 | MEN1 (0.38) | ALDH1A1MEN1KMT2ANOS3NOS1 | |
| SCHEMBL24819998 | 0.81 | MEN1 (0.38) | ALDH1A1MEN1KMT2ANOS3NOS1 | |
| SCHEMBL24822696 | 0.81 | MEN1 (0.38) | ALDH1A1MEN1KMT2ANOS3NOS1 | |
| SCHEMBL783666 | 0.81 | SLC6A2 (0.48) | ALDH1A1MEN1KMT2ANOS3NOS1 | |
| SCHEMBL13573738 | 0.81 | MEN1 (0.38) | ALDH1A1MEN1KMT2ANOS3NOS1 | |
| SCHEMBL13080848 | 0.81 | MEN1 (0.38) | ALDH1A1MEN1KMT2ANOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110650965-B | Dihydrocarbyl-silyl-bridged-1,3 disubstituted-2-indenyl metallocene complexes for olefin polymerization | SABIC环球技术有限责任公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-110650965-A | Dihydrocarbyl-silyl-bridged-1, 3 disubstituted-2-indenyl metallocene complexes for olefin polymerization | SABIC环球技术有限责任公司 | 2020-01-03 | — | — | CN | disclosed |