Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.54 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorobenzene SCHEMBL28345387 | 0.90 | HIF1A (0.57) | HIF1AEGLN1PSEN1PSEN2APH1B | |
| Fluorobenzene SCHEMBL28344654 | 0.89 | ROCK2 (0.51) | HIF1AEGLN1PSEN1PSEN2APH1B | |
| Fluorobenzene SCHEMBL28348078 | 0.87 | HIF1A (0.54) | HIF1AEGLN1PSEN1PSEN2APH1B | |
| Fluorobenzene SCHEMBL28347609 | 0.85 | HIF1A (0.66) | HIF1APSEN1PSEN2APH1BNCSTN | |
| Fluorobenzene SCHEMBL28347863 | 0.84 | HIF1A (0.54) | HIF1AEGLN1PSEN1PSEN2APH1B | |
| Fluorobenzene SCHEMBL28344695 | 0.83 | EGLN1 (0.65) | HIF1AEGLN1PSEN1PSEN2APH1B | |
| Fluorobenzene SCHEMBL28344741 | 0.82 | HIF1A (0.63) | HIF1AEGLN1PSEN1PSEN2APH1B | |
| Fluorobenzene SCHEMBL28347977 | 0.81 | HIF1A (0.50) | HIF1AEGLN1PSEN1PSEN2APH1B | |
| Fluorobenzene SCHEMBL28344624 | 0.81 | HIF1A (0.50) | HIF1AEGLN1PSEN1PSEN2APH1B | |
| SCHEMBL28348304 | 0.80 | HIF1A (0.81) | HIF1ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407824-A | Aryl methanamide compounds and preparation method thereof, pharmaceutical composition and purposes | UNIV ANHUI MEDICAL | 2019-11-05 | — | — | CN | disclosed |