Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 18/20 | 0.76 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | FPR1 | P21462 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16738197 | 1.00 | FPR2 (0.76) | FPR2RAB9AFPR1MEN1LMNA | |
| SCHEMBL16738207 | 0.88 | FPR2 (0.73) | FPR2RAB9AMEN1LMNAPOLB | |
| SCHEMBL16008504 | 0.88 | FPR2 (0.73) | FPR2RAB9AFPR1MEN1LMNA | |
| SCHEMBL28348394 | 0.88 | FPR2 (0.81) | FPR2RAB9AFPR1 | |
| SCHEMBL16738251 | 0.88 | FPR2 (0.81) | FPR2RAB9AFPR1 | |
| SCHEMBL14889982 | 0.87 | FPR2 (1.00) | FPR2RAB9AFPR1MEN1LMNA | |
| SCHEMBL14948917 | 0.87 | FPR2 (1.00) | FPR2RAB9AFPR1MEN1LMNA | |
| SCHEMBL14889619 | 0.86 | FPR2 (0.78) | FPR2 | |
| SCHEMBL19723124 | 0.86 | FPR2 (0.78) | FPR2 | |
| SCHEMBL16008281 | 0.85 | FPR2 (0.77) | FPR2RAB9AMEN1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106518742-B | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor-like-1 (FPRL-1) receptor modulators | 阿勒根公司 | 2020-01-21 | — | — | CN | disclosed |