Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | TGM1 | P22735 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21033830 | 0.78 | POLB (0.40) | TSHRPKMKMT2ACA12CA1 | |
| SCHEMBL7423339 | 0.77 | KDM4E (0.80) | KDM4EMAPTCYP3A4NFKB1LMNA | |
| SCHEMBL243961 | 0.74 | KDM4E (0.54) | KDM4EMAPTCYP3A4NFKB1LMNA | |
| SCHEMBL22339125 | 0.74 | KDM4E (0.54) | KDM4EMAPTCYP3A4NFKB1LMNA | |
| SCHEMBL14991003 | 0.74 | KDM4E (0.54) | KDM4EMAPTCYP3A4NFKB1LMNA | |
| SCHEMBL243962 | 0.74 | KDM4E (0.54) | KDM4EMAPTCYP3A4NFKB1LMNA | |
| SCHEMBL8228389 | 0.74 | KDM4E (0.48) | KDM4EMAPTCYP3A4NFKB1LMNA | |
| SCHEMBL31071498 | 0.73 | — | — | |
| SCHEMBL2989577 | 0.72 | KDM4E (0.52) | KDM4EMAPTCYP3A4NFKB1LMNA | |
| SCHEMBL3548115 | 0.72 | KDM4E (0.52) | KDM4EMAPTCYP3A4NFKB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590609-A | Fluorine-containing sulfonyl compound, intermediate, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2019-12-20 | — | — | CN | disclosed |