Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27833009 | 0.97 | KDM4E (0.50) | KDM4ELMNACYP3A4GABRA1TSHR | |
| Ethane SCHEMBL8042958 | 0.95 | KDM4E (0.48) | KDM4ELMNACYP3A4GABRA1TSHR | |
| Benzene SCHEMBL27821865 | 0.93 | KDM4E (0.46) | KDM4ELMNACYP3A4GABRA1TSHR | |
| SCHEMBL10815069 | 0.84 | — | — | |
| Dimethylformamide SCHEMBL27563362 | 0.83 | KDM4E (0.39) | KDM4ELMNACYP3A4GABRA1TSHR | |
| Dimethylformamide SCHEMBL27646174 | 0.82 | KDM4E (0.38) | KDM4ELMNACYP3A4GABRA1TSHR | |
| SCHEMBL1746338 | 0.78 | — | — | |
| SCHEMBL7423339 | 0.77 | KDM4E (0.80) | KDM4ELMNACYP3A4GABRA1TSHR | |
| SCHEMBL14991003 | 0.74 | KDM4E (0.54) | KDM4ELMNACYP3A4GABRA1TSHR | |
| SCHEMBL243961 | 0.74 | KDM4E (0.54) | KDM4ELMNACYP3A4GABRA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119699310-A | Application of cellulose-based material as biological cryoprotectant | 北京理工大学 | 2025-03-28 | — | — | CN | claimed |
| CN-117105883-A | Preparation method of piperazine sulfonic acid buffer | 苏州亚科科技股份有限公司 | 2023-11-24 | — | — | CN | claimed |
| CN-114865556-B | Light high-strength MPP corrugated pipe | 杭州富阳科威钢业有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-114634465-B | Pentadienone derivative containing sulfonyl piperazine as well as preparation method and application thereof | 贵州大学 | 2023-05-30 | — | — | CN | claimed |
| CN-110283282-B | Preparation method of functional hairbrush-shaped fluorescent microspheres | 上海工程技术大学 | 2022-08-26 | — | — | CN | claimed |
| CN-114865556-A | Light high-strength MPP corrugated pipe | 杭州富阳科威钢业有限公司 | 2022-08-05 | — | — | CN | claimed |
| CN-114634465-A | Sulfonyl piperazine-containing pentadiene ketone derivative and preparation method and application thereof | 贵州大学 | 2022-06-17 | — | — | CN | claimed |
| CN-114085199-A | Chalcone derivative containing sulfonyl piperazine and preparation method and application thereof | 贵州大学 | 2022-02-25 | — | — | CN | claimed |
| CN-110092734-A | A kind of 2-(phenylmethylene) malononitrile or derivatives thereof series connection synthetic method | 华侨大学 | 2019-08-06 | — | — | CN | claimed |
| US-7674810-B2 | 1,1-dioxo-1H-1Λ6-benzo[d]isothiazol-3-yl)-4-hydroxy-1,5-dihydro-pyrrol-2-one inhibitors of HCV polymerase | ROCHE PALO ALTO LLC (US) | 2010-03-09 | — | — | US | claimed |
| CN-101189230-A | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC (CH) | 2008-05-28 | — | — | CN | claimed |
| EP-1879885-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F. Hoffmann-Roche AG (CH) | 2008-01-23 | — | — | EP | claimed |
| US-20060252785-A1 | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC | 2006-11-09 | — | — | US | claimed |
| WO-2006117306-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-11-09 | — | — | WO | claimed |
| US-6971945-B2 | Multi-step polishing solution for chemical mechanical planarization | ROHM AND HAAS ELECTRONIC MATERIALS CMP HOLDINGS, INC. (US) | 2005-12-06 | — | — | US | claimed |
| US-20050194357-A1 | MULTI-STEP POLISHING SOLUTION FOR CHEMICAL MECHANICAL PLANARIZATION | ROHM AND HAAS ELECTRONIC MATERIALS CMP HOLDINGS, INC. | 2005-09-08 | — | — | US | claimed |
| US-3983117-A | OPTICAL BRIGHTENERS | BASF AKTIENGESELLSCHAFT (DT) | 1976-09-28 | — | — | US | claimed |
| US-3950340-A | POLYESTERS | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | claimed |
| CN-120923175-A | Preparation method of high-durability concrete pipe pile | 山东华威建筑科技有限公司 | 2025-11-11 | — | — | CN | disclosed |
| US-3950340-A | POLYESTERS | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252785-A1 | Heterocyclic antiviral compounds | EIF2AK2, HAVCR2, POLR2E | KDM4E 2075/4885LMNA 1768/4885CYP3A4 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.