Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.65 |
| ▸ | POU2F2 | P09086 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | POU2F1 | P14859 | 1/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.61 |
| ▸ | HRH2 | P25021 | 1/20 | 0.61 |
| ▸ | MC4R | P32245 | 1/20 | 0.61 |
| ▸ | FAP | Q12884 | 1/20 | 0.61 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.61 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.61 |
| ▸ | GHSR | Q92847 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL556151 | 0.92 | DPP4 (0.77) | DPP4CHRM1POU2F2ADORA3POU2F1 | |
| SCHEMBL28346678 | 0.92 | DPP4 (0.77) | DPP4CHRM1POU2F2ADORA3POU2F1 | |
| SCHEMBL28752138 | 0.90 | DPP4 (0.82) | DPP4CHRM1POU2F2ADORA3POU2F1 | |
| SCHEMBL556428 | 0.89 | DPP4 (0.82) | DPP4CHRM1POU2F2ADORA3POU2F1 | |
| SCHEMBL555576 | 0.86 | DPP4 (0.76) | DPP4CHRM1POU2F2ADORA3POU2F1 | |
| SCHEMBL28347270 | 0.86 | DPP4 (0.68) | DPP4CHRM1POU2F2ADORA3POU2F1 | |
| SCHEMBL555521 | 0.85 | DPP4 (0.85) | DPP4CHRM1CHRM3 | |
| SCHEMBL3968118 | 0.84 | DPP4 (0.83) | DPP4CHRM1POU2F2ADORA3POU2F1 | |
| SCHEMBL3968112 | 0.84 | DPP4 (0.83) | DPP4CHRM1POU2F2ADORA3POU2F1 | |
| SCHEMBL555925 | 0.84 | DPP4 (0.81) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108299436-B | Xanthine compound and pharmaceutical composition and application thereof | 上海慈瑞医药科技股份有限公司 | 2020-01-17 | — | — | CN | disclosed |