⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4543148 | 0.77 | — | — | |
| SCHEMBL29017589 | 0.75 | — | — | |
| SCHEMBL21181266 | 0.64 | — | — | |
| SCHEMBL14740931 | 0.62 | — | — | |
| SCHEMBL17847691 | 0.62 | — | — | |
| SCHEMBL4033993 | 0.60 | — | — | |
| SCHEMBL21295151 | 0.60 | — | — | |
| SCHEMBL3767412 | 0.57 | — | — | |
| SCHEMBL9715235 | 0.57 | — | — | |
| SCHEMBL25429315 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073424-A | Histone deacetylase inhibitor and application thereof | 微境生物医药科技(上海)有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-114667143-A | Composition for preventing or inhibiting axonal degeneration | 将军治疗有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-106478564-B | Cathepsin K inhibitors and uses thereof | 广东东阳光药业有限公司 | 2021-11-12 | — | — | CN | disclosed |
| CN-113412112-A | Organophosphorus substituted compounds as c-MET inhibitors and therapeutic uses thereof | 贝达医药公司 | 2021-09-17 | — | — | CN | disclosed |
| CN-113121393-A | Aromatic amide compound and application thereof in medicines | 广东东阳光药业有限公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-113121463-A | Amide compound with bicyclic structure and application thereof in medicines | 广东东阳光药业有限公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-108779104-B | Novel compounds for inhibiting nicotinamide phosphoribosyltransferase and compositions containing same | 将军治疗有限公司 | 2021-04-13 | — | — | CN | disclosed |
| CN-111788193-A | PD-1/PD-L1 small molecule inhibitor and application thereof in medicines | 广东东阳光药业有限公司 | 2020-10-16 | — | — | CN | disclosed |
| CN-105524053-B | Tetrahydrobenzothiophene compounds | 广东东阳光药业有限公司 | 2020-06-05 | — | — | CN | disclosed |
| CN-105461709-B | Substituted urea derivatives and their use in medicine | 广东东阳光药业有限公司 | 2020-01-21 | — | — | CN | disclosed |