SCHEMBL28351102

SCHEMBL28351102

Nc1ccccc1-c1cccc2c3ccccc3c3ccccc3c12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.62
L3MBTL1 Q9Y468 3/20 0.62
KEAP1 Q14145 2/20 0.56
CRHBP P24387 1/20 0.56
CRHR2 Q13324 1/20 0.56
NFE2L2 Q16236 1/20 0.56
HSD17B10 Q99714 6/20 0.48
HPGD P15428 5/20 0.48
TSHR P16473 4/20 0.48
CYP3A4 P08684 4/20 0.48
TDP1 Q9NUW8 2/20 0.48
CASP1 P29466 3/20 0.43
MAPK1 P28482 2/20 0.43
HIF1A Q16665 1/20 0.43
HKDC1 Q2TB90 1/20 0.42
CYP1A2 P05177 2/20 0.42
THRB P10828 2/20 0.42
ADORA2A P29274 2/20 0.41
CASP7 P55210 2/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16623899 0.85 ALDH1A1 (0.77) ALDH1A1L3MBTL1KEAP1CRHBPCRHR2
SCHEMBL31025695 0.84 ALDH1A1 (0.55) ALDH1A1L3MBTL1KEAP1CRHBPCRHR2
SCHEMBL30241384 0.84 ALDH1A1 (0.55) ALDH1A1L3MBTL1KEAP1CRHBPCRHR2
SCHEMBL1007545 0.84 ALDH1A1 (0.55) ALDH1A1L3MBTL1KEAP1CRHBPCRHR2
SCHEMBL1351306 0.79 ALDH1A1 (0.58) ALDH1A1L3MBTL1KEAP1CRHBPCRHR2
SCHEMBL31607672 0.79 ALDH1A1 (1.00) ALDH1A1L3MBTL1HSD17B10HPGDTSHR
SCHEMBL169281 0.79 ALDH1A1 (1.00) ALDH1A1L3MBTL1HSD17B10HPGDTSHR
SCHEMBL21074055 0.77 ALDH1A1 (0.50) ALDH1A1L3MBTL1KEAP1CRHBPCRHR2
SCHEMBL56035 0.76 ALDH1A1 (0.65) ALDH1A1L3MBTL1KEAP1CRHBPCRHR2
SCHEMBL29521589 0.76 ALDH1A1 (0.65) ALDH1A1L3MBTL1KEAP1CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110698458-A Organic luminescent material and application thereof 烟台显华化工科技有限公司 2020-01-17 CN disclosed