Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5784743 | 0.84 | FFAR3 (0.41) | FFAR3LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL2461092 | 0.81 | CA12 (0.36) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11649571 | 0.79 | FFAR3 (0.37) | FFAR3LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL2465652 | 0.77 | — | — | |
| SCHEMBL2077132 | 0.73 | FFAR3 (0.37) | FFAR3LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL6223657 | 0.71 | FFAR3 (0.35) | FFAR3LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL28947878 | 0.70 | CHRM1 (0.33) | FFAR3ALDH1A1 | |
| SCHEMBL633119 | 0.69 | TDP1 (0.32) | — | |
| SCHEMBL1903729 | 0.69 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| SCHEMBL23295107 | 0.69 | FFAR3 (0.35) | FFAR3LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030739-A1 | POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF | ABBOTT LABORATORIES (US) | 2010-03-18 | — | — | WO | disclosed |
| WO-2010030730-A1 | POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF | ABBOTT LABORATORIES (US) | 2010-03-18 | — | — | WO | disclosed |
| WO-2009129385-A1 | CATIONIC LIPIDS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2009-10-22 | — | — | WO | disclosed |
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |