SCHEMBL28352004

SCHEMBL28352004

CC(C)CC(NC(=O)Nc1ccc(Br)cc1)C(=O)NC(C(=O)O)C(C)(C)C

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 16/20 0.71
MEN1 O00255 1/20 0.55
LMNA P02545 1/20 0.55
POLB P06746 1/20 0.55
KMT2A Q03164 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
ANPEP P15144 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16588632 1.00 FPR2 (0.71) FPR2MEN1LMNAPOLBKMT2A
SCHEMBL16588654 1.00 FPR2 (0.71) FPR2MEN1LMNAPOLBKMT2A
SCHEMBL16588630 0.86 FPR2 (0.74) FPR2LMNAANPEP
SCHEMBL16588637 0.86 FPR2 (0.64) FPR2LMNAANPEP
SCHEMBL28351945 0.86 FPR2 (0.64) FPR2LMNAANPEP
SCHEMBL28348567 0.86 FPR2 (0.74) FPR2LMNAANPEP
SCHEMBL28351954 0.86 FPR2 (0.71) FPR2MEN1LMNAPOLBKMT2A
SCHEMBL16588770 0.86 FPR2 (0.71) FPR2MEN1LMNAPOLBKMT2A
SCHEMBL14890089 0.86 FPR2 (0.74) FPR2ANPEP
SCHEMBL20983170 0.86 FPR2 (0.74) FPR2ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106518742-B Amide derivatives of N-urea substituted amino acids as formyl peptide receptor-like-1 (FPRL-1) receptor modulators 阿勒根公司 2020-01-21 CN disclosed