Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29083270 | 0.88 | KDR (0.57) | KDRBRAF | |
| SCHEMBL4330373 | 0.87 | KDR (0.52) | KDRBRAF | |
| SCHEMBL27713157 | 0.87 | KDR (0.60) | KDRBRAF | |
| SCHEMBL29251625 | 0.86 | GCK (0.52) | KDRBRAF | |
| SCHEMBL15541633 | 0.84 | KDR (0.43) | KDRBRAF | |
| SCHEMBL16895229 | 0.84 | KDR (0.59) | KDRBRAF | |
| SCHEMBL4333626 | 0.84 | KDR (0.48) | KDRBRAF | |
| SCHEMBL4730615 | 0.83 | HSPB1 (0.49) | KDRBRAF | |
| SCHEMBL4335111 | 0.83 | GCK (0.49) | KDRBRAF | |
| SCHEMBL28593422 | 0.83 | GCK (0.47) | KDRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343046-A | Novel 3-oxo-4-substituted aryl-3, 4-dihydropyrazine-2-carboxamide compound and application thereof | 辽宁大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-113999205-B | Pyridine compound containing triazolone amide and imidazolone amide structures and application thereof | 辽宁大学 | 2023-09-15 | — | — | CN | disclosed |
| CN-111440177-B | Substituted pyrazolo [1,5-a ] pyrimidine compound and preparation method and application thereof | 辽宁大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-110218205-B | 2, 4-diarylaminopyrimidine derivatives containing pyridine structure and application thereof | 辽宁大学 | 2022-04-05 | — | — | CN | disclosed |
| CN-113999205-A | Pyridine compound containing triazole ketoamide and imidazole amide structures and application thereof | 辽宁大学 | 2022-02-01 | — | — | CN | disclosed |
| CN-108329258-B | Semicarbazone structure-containing 4-phenoxypyridine derivative and application thereof | 辽宁大学 | 2021-04-13 | — | — | CN | disclosed |
| CN-111440177-A | Novel substituted pyrazolo [1,5-a ] pyrimidine compound and preparation method and application thereof | 辽宁大学 | 2020-07-24 | — | — | CN | disclosed |
| CN-111303121-A | 4-phenoxypyridine compound containing quinoxalinone and application thereof | 辽宁大学 | 2020-06-19 | — | — | CN | disclosed |
| CN-110684013-A | 4-phenoxypyridine derivatives containing 3-pyridazinone, 4-pyridazinone and 1,2, 4-triazinone structures and application thereof | 辽宁大学 | 2020-01-14 | — | — | CN | disclosed |