Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.72 |
| ▸ | RORC | P51449 | 17/20 | 0.47 |
| ▸ | PRKCB | P05771 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28352086 | 1.00 | KCNH2 (0.72) | KCNH2RORCPRKCBGRM5 | |
| SCHEMBL28883114 | 0.94 | KCNH2 (0.81) | KCNH2RORCPRKCB | |
| SCHEMBL28883115 | 0.94 | KCNH2 (0.81) | KCNH2RORCPRKCB | |
| SCHEMBL18822951 | 0.90 | KCNH2 (0.70) | KCNH2RORCPRKCB | |
| SCHEMBL17294257 | 0.89 | KCNH2 (0.90) | KCNH2RORC | |
| SCHEMBL17294256 | 0.89 | KCNH2 (0.90) | KCNH2RORC | |
| SCHEMBL17294426 | 0.88 | KCNH2 (0.66) | KCNH2RORCPRKCB | |
| SCHEMBL17294424 | 0.88 | KCNH2 (0.66) | KCNH2RORCPRKCB | |
| SCHEMBL15777536 | 0.88 | KCNH2 (0.79) | KCNH2RORCPRKCBGRM5 | |
| SCHEMBL15783881 | 0.88 | KCNH2 (0.79) | KCNH2RORCPRKCBGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106536489-B | Retinoid-related orphan receptor gamma modulators and uses thereof | 葛兰素史密斯克莱知识产权发展有限公司 | 2020-02-07 | — | — | CN | disclosed |