Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.81 |
| ▸ | RORC | P51449 | 15/20 | 0.55 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883114 | 1.00 | KCNH2 (0.81) | KCNH2RORCPRKCBCHRM2CHRM1 | |
| SCHEMBL28352091 | 0.94 | KCNH2 (0.72) | KCNH2RORCPRKCB | |
| SCHEMBL28352086 | 0.94 | KCNH2 (0.72) | KCNH2RORCPRKCB | |
| SCHEMBL15783881 | 0.94 | KCNH2 (0.79) | KCNH2RORCPRKCB | |
| SCHEMBL15777536 | 0.94 | KCNH2 (0.79) | KCNH2RORCPRKCB | |
| SCHEMBL17182395 | 0.91 | KCNH2 (0.78) | KCNH2RORCPRKCB | |
| SCHEMBL15777823 | 0.91 | KCNH2 (0.78) | KCNH2RORCPRKCB | |
| SCHEMBL15783894 | 0.90 | KCNH2 (0.76) | KCNH2RORCPRKCB | |
| SCHEMBL15777827 | 0.90 | KCNH2 (1.00) | KCNH2RORC | |
| SCHEMBL15783893 | 0.90 | KCNH2 (0.78) | KCNH2RORCPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001342-B | Novel compounds | 葛兰素史密斯克莱知识产权发展有限公司 | 2020-02-07 | — | — | CN | disclosed |