Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | RORC | P51449 | 6/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.35 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28352107 | 1.00 | KCNH2 (0.44) | KCNH2RORCPTGDR2MGLLFAAH | |
| SCHEMBL17294383 | 0.87 | KCNH2 (0.59) | KCNH2RORC | |
| SCHEMBL17294431 | 0.87 | KCNH2 (0.51) | KCNH2RORCPTGDR2CHRM4 | |
| SCHEMBL17294434 | 0.87 | KCNH2 (0.51) | KCNH2RORCPTGDR2CHRM4 | |
| SCHEMBL17294381 | 0.87 | KCNH2 (0.59) | KCNH2RORC | |
| SCHEMBL18787518 | 0.86 | KCNH2 (0.41) | KCNH2RORCPTGDR2MTORRPTOR | |
| SCHEMBL17298113 | 0.86 | KCNH2 (0.41) | KCNH2RORCPTGDR2MTORRPTOR | |
| SCHEMBL21354240 | 0.85 | RORC (0.41) | KCNH2RORCPTGDR2MGLLFAAH | |
| SCHEMBL21354238 | 0.83 | PTGDR2 (0.49) | RORCPTGDR2MGLL | |
| SCHEMBL28356264 | 0.83 | PTGDR2 (0.49) | RORCPTGDR2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106536489-B | Retinoid-related orphan receptor gamma modulators and uses thereof | 葛兰素史密斯克莱知识产权发展有限公司 | 2020-02-07 | — | — | CN | disclosed |