SCHEMBL28352175

SCHEMBL28352175

CSCC[C@@H]1NC(=O)NC1=O

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 2/20 0.56
GAA P10253 2/20 0.40
KMT2A Q03164 1/20 0.40
TSHR P16473 1/20 0.40
MAPT P10636 3/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ADAMTS5 Q9UNA0 5/20 0.35
ADAMTS4 O75173 2/20 0.35
ADAM10 O14672 1/20 0.34
MMP12 P39900 1/20 0.34
ADAM17 P78536 1/20 0.34
ADAM9 Q13443 1/20 0.34
POLB P06746 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL41055 1.00 HDAC8 (0.56) HDAC8GAAKMT2ATSHRMAPT
SCHEMBL28702424 0.98 HDAC8 (0.54) HDAC8GAAKMT2ATSHRMAPT
SCHEMBL28711685 0.98 HDAC8 (0.54) HDAC8GAAKMT2ATSHRMAPT
SCHEMBL29419662 0.98 HDAC8 (0.54) HDAC8GAAKMT2ATSHRMAPT
Potassium SCHEMBL29847318 0.98 HDAC8 (0.54) HDAC8GAAKMT2ATSHRMAPT
Bicarbonate SCHEMBL28869061 0.91 HDAC8 (0.49) HDAC8GAAKMT2ATSHRMAPT
Bicarbonate SCHEMBL29046515 0.90 HDAC8 (0.47) HDAC8GAAKMT2ATSHRMAPT
SCHEMBL942516 0.83 TSHR (0.38) HDAC8GAAKMT2ATSHRALDH1A1
SCHEMBL18055747 0.83 TSHR (0.38) HDAC8GAAKMT2ATSHRALDH1A1
SCHEMBL18055748 0.83 TSHR (0.38) HDAC8GAAKMT2ATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114163367-A Methionine environment-friendly preparation method based on carbon dioxide acidification method 宁夏紫光天化蛋氨酸有限责任公司 2022-03-11 CN claimed
CN-114163367-A Methionine environment-friendly preparation method based on carbon dioxide acidification method 宁夏紫光天化蛋氨酸有限责任公司 2022-03-11 CN disclosed
CN-110714035-A Method for preparing D-aliphatic amino acid by cascade reaction 江南大学 2020-01-21 CN disclosed