Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 5/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.35 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28352175 | 1.00 | HDAC8 (0.56) | HDAC8GAAKMT2ATSHRMAPT | |
| SCHEMBL28702424 | 0.98 | HDAC8 (0.54) | HDAC8GAAKMT2ATSHRMAPT | |
| SCHEMBL28711685 | 0.98 | HDAC8 (0.54) | HDAC8GAAKMT2ATSHRMAPT | |
| SCHEMBL29419662 | 0.98 | HDAC8 (0.54) | HDAC8GAAKMT2ATSHRMAPT | |
| Potassium SCHEMBL29847318 | 0.98 | HDAC8 (0.54) | HDAC8GAAKMT2ATSHRMAPT | |
| Bicarbonate SCHEMBL28869061 | 0.91 | HDAC8 (0.49) | HDAC8GAAKMT2ATSHRMAPT | |
| Bicarbonate SCHEMBL29046515 | 0.90 | HDAC8 (0.47) | HDAC8GAAKMT2ATSHRMAPT | |
| SCHEMBL942516 | 0.83 | TSHR (0.38) | HDAC8GAAKMT2ATSHRALDH1A1 | |
| SCHEMBL18055747 | 0.83 | TSHR (0.38) | HDAC8GAAKMT2ATSHRALDH1A1 | |
| SCHEMBL18055748 | 0.83 | TSHR (0.38) | HDAC8GAAKMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12512186-B2 | Method and system for process control | EVONIK OPERATIONS GMBH (DE) | 2025-12-30 | — | — | US | claimed |
| US-12391969-B2 | Additive used in methionine preparation process, and methionine preparation method | ZHEJIANG NHU CO., LTD. (CN) | 2025-08-19 | — | — | US | claimed |
| CN-114163367-B | Environment-friendly methionine preparation method based on carbon dioxide acidification method | 宁夏紫光天化蛋氨酸有限责任公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119403784-A | Method for obtaining a mixture containing methionine and potassium bicarbonate | 赢创运营有限公司 | 2025-02-07 | — | — | CN | claimed |
| US-12195422-B2 | Process for the preparation of D,L-methionine | EVONIK OPERATIONS GMBH (DE) | 2025-01-14 | — | — | US | claimed |
| US-12187669-B2 | Method for producing methionine | EVONIK OPERATIONS GMBH (DE) | 2025-01-07 | — | — | US | claimed |
| CN-114149351-B | Methionine optimizing preparation method based on sulfuric acid direct acidification method and sodium sulfate washing equipment | 宁夏紫光天化蛋氨酸有限责任公司 | 2024-12-10 | — | — | CN | claimed |
| US-20240217925-A1 | Method for producing methionine | ADISSEO FRANCE S.A.S. (FR) | 2024-07-04 | — | — | US | claimed |
| CN-114853644-B | Method for preparing acetylmethionine by using saponification liquid | 宁夏紫光天化蛋氨酸有限责任公司 | 2024-06-14 | — | — | CN | claimed |
| EP-3617188-B1 | METHIONINE PRODUCTION METHOD AND PRODUCTION EQUIPMENT | SUMITOMO CHEMICAL CO (JP) | 2024-05-29 | — | — | EP | claimed |
| US-4303621-A | Process for the recovery of methionine and potassium bicarbonate | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1981-12-01 | — | — | US | claimed |
| US-4272631-A | Hydrolysis of 5-(beta-methylmercaptoethyl)-hydantoin | DIAMOND SHAMROCK CORPORATION (US) | 1981-06-09 | — | — | US | claimed |
| US-4259525-A | ALKALINE HYDROLYSIS OF 5-BETA-METHYLMERCAPTOETHYL-HYDANTOIN | DIAMOND SHAMROCK CORPORATION (US) | 1981-03-31 | — | — | US | claimed |
| US-4233461-A | DECOLORIZING WITH A REDUCING SULFUR COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-11-11 | — | — | US | claimed |
| US-4148688-A | Process for preparing L-methionine | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1979-04-10 | — | — | US | claimed |
| US-4094741-A | CULTURES, ASYMMETRIC HYDROLYSIS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1978-06-13 | — | — | US | claimed |
| US-4082767-A | CATALYTIC HYDROLYSIS OF HYDANTOIN COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-04-04 | — | — | US | claimed |
| US-4069251-A | Continuous process for the manufacture of methionine | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1978-01-17 | — | — | US | claimed |
| US-3980653-A | Process for the production of 3,6-bis-(2-methylmercaptoethyl)-2,5-piperazinedione | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-09-14 | — | — | US | claimed |
| US-3931307-A | Process for the stabilization of methionine | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-01-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12391969-B2 | Additive used in methionine preparation process, and methionine preparation method | MPHOSPH6, MMAB, MSRB3 | HDAC8 4864/4885GAA 4550/4885KMT2A 2658/4885 |
| US-20240217925-A1 | Method for producing methionine | BHMT2, BHMT, MGMT | HDAC8 2453/4885GAA 2988/4885KMT2A 444/4885 |
| US-12187669-B2 | Method for producing methionine | MGMT, MB, BHMT2 | HDAC8 4169/4885GAA 3661/4885KMT2A 1666/4885 |
| US-12512186-B2 | Method and system for process control | HVCN1, TASP1, BHMT2 | HDAC8 3704/4885GAA 4694/4885KMT2A 489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.