Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 3/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | THPO | P40225 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669156 | 0.98 | SCN1A (0.52) | SCN1ASCN2ASCN3ALMNAKCNH2 | |
| SCHEMBL4667514 | 0.92 | SCN1A (0.53) | SCN1ASCN2ASCN3ALMNAKCNH2 | |
| SCHEMBL4670218 | 0.88 | SCN1A (0.61) | SCN1ASCN2ASCN3ALMNAKCNH2 | |
| SCHEMBL4556683 | 0.84 | SCN1A (0.57) | SCN1ASCN2ASCN3ALMNAKCNH2 | |
| SCHEMBL4669231 | 0.83 | SLC6A2 (0.61) | SCN1ASCN2ASCN3ALMNAKCNH2 | |
| SCHEMBL7962993 | 0.81 | SLC6A2 (0.50) | SCN1ASCN2ASCN3ALMNAKCNH2 | |
| SCHEMBL21861450 | 0.81 | SLC6A2 (0.50) | SCN1ASCN2ASCN3ALMNAKCNH2 | |
| SCHEMBL21861456 | 0.81 | SCN1A (0.50) | SCN1ASCN2ASCN3ALMNAKCNH2 | |
| SCHEMBL7958769 | 0.81 | SLC6A2 (0.50) | SCN1ASCN2ASCN3ALMNAKCNH2 | |
| SCHEMBL28676094 | 0.81 | KCNH2 (0.55) | SCN1ASCN2ASCN3ALMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107739433-B | Hydroxyl-terminated phosphorus-containing polyester, preparation method and application thereof, and halogen-free flame-retardant reinforced toughened epoxy composite material | 四川大学 | 2020-02-07 | — | — | CN | disclosed |